Improvement of Total Flavonoids from Dracocephalum moldavica L. in Rats with Chronic Mountain Sickness through 1H-NMR Metabonomics
نویسندگان
چکیده
منابع مشابه
Effects and mechanisms of acetyl-L-cysteine in rats with chronic mountain sickness with H1-NMR metabolomics methods
BACKGROUND We established a rat model of chronic mountain sickness using acetyl-L-cysteine. Then we studied the effects and mechanisms of acetyl-L-cysteine (Da) in rats with chronic mountain sickness using nuclear magnetic resonance (H1-NMR) metabolomics methods. MATERIAL AND METHODS Using NMR spectroscopy combined with pattern recognition and orthogonal partial least squares discriminant ana...
متن کاملDevelopment of solid lipid nanoparticles containing total flavonoid extract from Dracocephalum moldavica L. and their therapeutic effect against myocardial ischemia–reperfusion injury in rats
Total flavonoid extract from Dracocephalum moldavica L. (TFDM) contains effective components of D. moldavica L. that have myocardial protective function. However, the cardioprotection function of TFDM is undesirable due to its poor solubility. In order to improve the solubility and efficacy of TFDM, we developed TFDM-loaded solid lipid nanoparticles (TFDM-SLNs) and optimized the formulation of ...
متن کاملChronic Mountain Sickness
Introduction Chronic mountain sickness (CMS) affects people who are native or long time residents of high altitude. It is characterized by an excessive erythrocytosis for the altitude of residence, severe hypoxemia and in many cases, particularly in severe CMS, high altitude pulmonary hypertension (HAPH). CMS usually begins insidiously in adult life associated probably to aging; the clinical pi...
متن کاملChronic mountain sickness.
I read with great interest the article by White et al,’ which appeared in the July 1991 issue ofChest. The authors raised several important points concerning the utility of chest radiographs in adults admitted for exacerbations of bronchial asthma, I feel, however, that several aspects oftheir study must be addressed. First ofall, the study is relatively small (n =58) and uncontrolled, and invo...
متن کاملPathology of chronic mountain sickness.
Arias-Stella, J., Kriiger, H., and Recavarren, S. (1973). Thorax, 28, 701-708. Pathology of chronic mountain sickness. Pathological data on chronic mountain sickness are scarce due to the fact that the disease is ameliorated or cured by descent to a low altitude. In this report we describe a case of chronic mountain sickness occurring in a woman of 48 years at Cerro de Pasco (4,300 m above sea ...
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ژورنال
عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine
سال: 2021
ISSN: 1741-4288,1741-427X
DOI: 10.1155/2021/6695346